Πρότυπο:Πληροφορίες φαρμάκου

Πληροφορίες φαρμάκου

Τεκμηρίωση προτύπου[προβολή] [επεξεργασία] [ιστορικό] [ανανέωση]

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{{Infobox drug}} or {{Drugbox}} is the infobox for drugs, both medical and recreational. It can be used for single chemicals (most common), and for #Combination products, #Monoclonal antibody drugs and #Vaccines.

Type of drug

Single chemical (type=)

Drugs that are a simple chemical compound (about 90% of the drug articles are). Short parameter list:

{{Infobox drug
| drug_name         =
| INN               =
| type              =<!-- empty -->
| IUPAC_name        = 
| image             = 
| alt               = 
| caption           =
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_AU_comment = 
| pregnancy_US      = <!-- A/B/C/D/X/N -->
| pregnancy_category= 
| routes_of_administration = 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_BR =  <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F-->
| legal_BR_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_DE = <!-- Anlage I, II, III -->
| legal_NZ = <!-- Class A, B, C -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C -->
| legal_US = <!-- OTC/Rx-only/Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_status      = <!-- Free text -->
<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| metabolites       =
| onset             = 
| elimination_half-life = 
| duration_of_action =
| excretion         = 
<!-- Identifiers -->
| CAS_number        = 
| class             = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
<!-- Chemical and physical data -->
| chemical_formula  = 
| molecular_weight  = 
}}

Full single-drug template with extended fields:

{{Infobox drug
| drug_name         =
| INN               =
| type              =<!-- empty -->
| IUPAC_name        = 
| image             = 
| width             = 
| alt               = 
| image2            = 
| width2            = 
| alt2              = 
| imageL            =
| widthL            =
| altL              = 
| imageR            = 
| widthR            = 
| altR              = 
| caption           = 
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_CA        = <!-- Health Canada may use generic or brand name (generic name preferred) -->
| licence_EU        = <!-- EMA requires brand name -->
| DailyMedID       = <!-- DailyMed may use generic or brand name (generic name preferred) -->
| licence_US        = <!-- FDA may use generic or brand name (generic name preferred) -->
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_AU_comment =      
| pregnancy_US      = <!-- A / B / C / D / X / N -->
| pregnancy_US_comment = 
| pregnancy_category= 
| dependency_liability = 
| addiction_liability = 
| routes_of_administration = 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment = 
| legal_BR =  <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F-->
| legal_BR_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_CA_comment = 
| legal_DE = <!-- Anlage I, II, III or Unscheduled-->
| legal_DE_comment = 
| legal_NZ = <!-- Class A, B, C -->
| legal_NZ_comment = 
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C -->
| legal_UK_comment = 
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_US_comment = 
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_UN_comment = 
| legal_status      = <!--For countries not listed above-->
<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| metabolites       =
| onset             = 
| elimination_half-life = 
| duration_of_action =
| excretion         =
<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| class             = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChem           = 
| PubChemSubstance  = 
| IUPHAR_ligand     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
| NIAID_ChemDB      =
| PDB_ligand        = 
| synonyms          = 
<!-- Chemical and physical data -->
| chemical_formula  = 
| C= | H= | Ag= | Al= | As= | Au= | B= | Bi= | Br= | Ca= | Cl= | Co= | F= | Fe= | Gd= | I=
| K= | Li= | Mg= | Mn= | N= | Na= | O= | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn= | charge=
| molecular_weight  = 
| SMILES            = 
| Jmol              = 
| StdInChI          = 
| StdInChI_comment  = 
| StdInChIKey       = 
| density           = 
| density_notes     = 
| melting_point     = 
| melting_high      = 
| melting_notes     = 
| boiling_point     = 
| boiling_notes     = 
| solubility        = 
| sol_units         = 
| specific_rotation = 
}}

OR alternatively: use Diberri & Boghog's excellent Wikipedia template filling tool which will generate a populated template to copy & paste into an article if "DrugBank ID" is selected in the dropdown menu and a DrugBank ID number (which may be obtained from DrugBank search) is added in the adjacent field. Please select for Fill template vertically, but as Wikipedia is a general encyclopedia, most drugs do not warrant Show extended fields.

Combination of drugs (type=combo)

For drug-combinations, at least two components must be defined, with optional a 3rd and 4th component. For each component:

| component1 =<!-- name, will be wikilinked -->
| class1     =<!-- class of agent, needs manual wikilinking -->

Example for Seretide:

Seretide

Συνδυασμός από
Fluticasone	Glucocorticoid
Salmeterol	Long-acting beta2 agonist

| drug_name  = Seretide
| type       = combo
| component1 = Fluticasone
| class1     = [[Glucocorticoid]]
| component2 = Salmeterol
| class2     = [[Beta2-adrenergic receptor agonist|Long-acting beta2 agonist]]

Generally combination articles will not need to display the molecular images of its constituents (the relevant specific articles would have the images). It disables all Chemical & Pharmacology parameters (which describe properties of single drug items). These redundant disabled parameters are best not included in the template calling, so use the following abridged forms of the template:

Shortened combination product form:

{{Infobox drug
| drug_name         =
| type              = combo
| component1        = <!-- Drugname, automatically linked -->
| class1            = <!-- Group, manual link using [[..|..]] -->
| component2        = <!-- Drugname, automatically linked -->
| class2            = <!-- Group, manual link using [[..|..]] -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      = <!-- A/B/C/D/X -->
| pregnancy_category= 
| legal_AU          = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_BR =  <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F-->
| legal_BR_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_NZ = <!--Class A, B, C -->
| legal_status      = 
| routes_of_administration = 
<!-- Identifiers -->
| CAS_number        = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
}}

Full combination product template with extended fields and allowing for up to 4 items:

{{Infobox drug
| drug_name         = 
| type              = combo
| component1        = <!-- Drugname, automatically linked -->
| class1            = <!-- Group, manual link using [[..|..]] -->
| component2        = <!-- Drugname, automatically linked -->
| class2            = <!-- Group, manual link using [[..|..]] -->
| component3        = <!-- Drugname, automatically linked -->
| class3            = <!-- Group, manual link using [[..|..]] -->
| component4        = <!-- Drugname, automatically linked -->
| class4            = <!-- Group, manual link using [[..|..]] -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_CA        = <!-- Health Canada may use generic or brand name (generic name preferred) -->
| licence_EU        = <!-- EMA requires brand name -->
| DailyMedID       = <!-- DailyMed may use generic or brand name (generic name preferred) -->
| licence_US        = <!-- FDA may use generic or brand name (generic name preferred) -->
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      = <!-- A/B/C/D/X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_BR =  <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F-->
| legal_BR_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status      = 
| dependency_liability = 
| addiction_liability = 
| routes_of_administration = 
<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChem           = 
| PubChemSubstance  = 
| IUPHAR_ligand     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
| synonyms          = 
}}

Monoclonal antibody drugs (type=mab)

• |type=mab

This form the box uses parameters:

| type       = mab
| mab_type   =
| source     =
| target     =

For example Catumaxomab:

Catumaxomab

Μονοκλωνικό αντίσωμα
Είδος	Trifunctional antibody
Πηγή	Rat/mouse hybrid
Στόχος	EpCAM, CD3

| type       = mab
| mab_type   = 3funct
| source     = axo
| target     = [[EpCAM]], [[CD3 (immunology)|CD3]]

mab_type defines one of the following types of antibody or antibody fragment:

mab_type	output
mab	Whole antibody
Fab	Fab fragment
F(ab')2	F(ab')2 fragment
Fab'	Fab' fragment
scFv	Single-chain variable fragment
di-scFv	Di-single-chain variable fragment
sdAb	Single domain antibody
3funct	Trifunctional antibody
clFab	Chemically linked Fab
BiTE	Bi-specific T-cell engager

source is the species on which the protein sequence of the antibody is based:

source	output
a	Rat
e	Hamster
i	Primate
o	Mouse
u	Human
xi/a, xi/e, etc.	Chimeric (rat/human) etc.
xi	Chimeric [generic, use only if values above are not applicable]
zu/a, zu/e, etc.	Humanized (from rat) etc.
zu	Humanized [generic, use only if values above are not applicable]
xizu/a, xizu/e, etc.	Chimeric/humanized hybrid (rat/human) etc.
xizu	Chimeric/humanized hybrid [generic, use only if values above are not applicable]
axo	Rat/mouse hybrid

target is the antigen at which the antibody is directed. This parameter takes free text as value, preferably including a wikilink such as |target=[[TNF-α]].

The drug name is followed by a "?" linked to Nomenclature of monoclonal antibodies, saving the need to explain how each monoclonal antibody has been named.

Shortened Monoclonal antibody form:

{{Infobox drug
| type              = mab
| image             = 
| alt               = 
| mab_type          = <!-- mab, Fab, F(ab')2, Fab', scFv, di-scFv, 3funct, clFab, BiTE -->
| source            = <!-- a, e, i, o, u, xi/a, zu/a, xizu/a, axo, ... -->
| target            = <!-- antigen, not the code number of the monoclonal antibody! -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      = <!-- A/B/C/D/X -->
| pregnancy_category=  
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled -->
| legal_AU_comment =
| legal_BR =  <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F-->
| legal_BR_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_NZ = <!--Class A, B, C -->
| legal_status      = 
| routes_of_administration = 
<!-- Pharmacokinetic data -->
| bioavailability   = 
| protein_bound     = 
| metabolism        = 
| metabolites       =
| onset             = 
| elimination_half-life = 
| duration_of_action=
| excretion         =
<!-- Identifiers -->
| CAS_number        = 
| ATC_prefix        = <!-- 'none' when not assigned -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
}}

Vaccines (type=vaccine)

• |type=vaccine

This allows the alternative parameters of the vaccine_type and target to be specified:

• target can be any text. CAn be used to link to a specific article
• vaccine_type must be from the defined list of options as described at Vaccine#Types, the infobox will provide standardised display and links as follows:

vaccine_type value	Output
killed or inactivated	Killed/Inactivated
attenuated	Attenuated virus
live	Live bacteria
toxoid	Toxoid
protein or protein subunit	Protein subunit
subunit	Subunit
conjugate	Conjugate vaccine
recombinant	Recombinant Vector
DNA	DNA vaccination

Where a vaccination product protects against more than one agent, please use the combination form of this infobox with type=combo (per #Combination products), and each classX=[[Vaccine]].

Shortened Vaccine form:

{{Infobox drug
| drug_name         = 
| type              = vaccine
| image             = 
| alt               = 
| target            = <!-- the antigen/bacteria/toxin/virus to protect against -->
| vaccine_type      = <!-- killed/attenuated/live/toxoid/protein subunit/subunit/conjugate/recombinant/DNA/mRNA -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| pregnancy_AU      = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      = <!-- A/B/C/D/X -->
| pregnancy_category=  
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_BR =  <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F-->
| legal_BR_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_NZ = <!--Class A, B, C -->
| legal_status      = 
| routes_of_administration = 
<!-- Identifiers -->
| CAS_number        = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| PubChem           = 
| DrugBank          = 
}}

Full Vaccine template with extended fields:

{{Infobox drug
| drug_name         =
| type              = vaccine
| image             = 
| alt               = 
| width             = 
| image2            = 
| alt2              = 
| width2            = 
| target            = <!-- the antigen/bacteria/toxin/virus to protect against -->
| vaccine_type      = <!-- killed/attenuated/live/toxoid/protein subunit/subunit/conjugate/recombinant/DNA/mRNA -->
<!-- Clinical data -->
| pronounce         =
| tradename         = 
| Drugs.com         = 
| MedlinePlus       = 
| licence_CA        = <!-- Health Canada may use generic or brand name (generic name preferred) -->
| licence_EU        = <!-- EMA requires brand name -->
| DailyMedID       = <!-- DailyMed may use generic or brand name (generic name preferred) -->
| licence_US        = <!-- FDA may use generic or brand name (generic name preferred) -->
| pregnancy_AU      =  <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_US      =  <!-- A/B/C/D/X -->
| pregnancy_category= 
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled—>
| legal_BR =  <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C4, C5, D1, D2, E, F-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_NZ = <!--Class A, B, C -->
| legal_status      = 
| dependency_liability = 
| addiction_liability =
| routes_of_administration = 
<!-- Identifiers -->
| CAS_number        = 
| CAS_supplemental  = 
| ATCvet            = 
| ATC_prefix        = <!-- 'none' if uncategorised -->
| ATC_suffix        = 
| ATC_supplemental  = 
| PubChem           = 
| PubChemSubstance  = 
| IUPHAR_ligand     = 
| DrugBank          = 
| ChemSpiderID      = 
| UNII              = 
| KEGG              = 
| ChEBI             = 
| ChEMBL            = 
| NIAID_ChemDB      =
}}

Parameters

See also: full parameter list

Infobox title and INN

Aspirin

By default, the title of the infobox is the article title. You can overwrite that using |drug_name=.

Per the Manual of Style, the infobox title must be the International nonproprietary name (INN). There is a tooltip text referring to INN.

When, for some reason, the title is not the INN, the correct INN can be added as a subtitle using |INN=

Heroin
INN: Diamorphine

 | drug_name = Heroin
 | INN = Diamorphine
 

When the drug has no INN at all, setting |INN=none will suppress the tooltip text mentioning INN.

See also #Names and identifiers

Images

You can use the image to provide an illustration. A caption can be added. The alt parameter is a textual description of the image, and is shown in the 'tooltip' and read by visually impaired readers (more in WP:ALT). Parameter width sets the width in px; default width is 200px.

demo: image

structure

| image            = Acetylsalicylsäure2.svg
| caption          = structure
| alt              = Molecule of aspirin
| width            = 125

A second image can be added using image2:

| image2            = 
| caption2          = 
| alt2              = 
| width2            = 

Also a side-by-side pair of images can be added (with single caption):

| imageL = 
| widthL = 
| altL = 
| imageR=
| widthR = 
| altR = 
| captionLR = 

See also |SMILES= input for the 3D model by Jmol (an external link).

Clinical data

| tradename =  
| Drugs.com =
| MedlinePlus =
| routes_of_administration =

• tradename – comma separated list of trade names by the originator (no generics, not more than three names)
• Drugs.com – link to Drugs.com monograph
• MedlinePlus – MedlinePlus drug accession number

Pregnancy category

See also pregnancy category, documentation for extensive documentation

Pregnancy Categorisation has been previously declared using just the pregnancy_category parameter with a variety of markup styles used to indicate various countries and their classifications. Alternatively pregnancy_AU and pregnancy_US may be set to the fixed categories. For Australia values permitted are: A, B1, B2, B3, C, D or X (note if just set to 'B' then B? is shown). For US values permitted are: A, B, C, D or X.

Note the UK does not have official designated categorisations, but has both a variety of standard phrases with explanatory qualifications, plus many individual descriptions. The generic |pregnancy_category= acceptts any text, and may be used with such country-specific information (non AU or US).

For the new US labeling guidelines PLLR, parameter |PLLR= is added and will show any input text (not re-formatted).

Demo pregnancy

Κλινικά δεδομένα
Κατηγορία ασφαλείας κύησης	AU: B1 any text US: C (Δεν έχει αποκλειστεί ο κίνδυνος) any text Used in pregnancy against PIH

  | pregnancy_AU = B1
  | pregnancy_AU_comment = any text
  | pregnancy_US = C
  | pregnancy_US_comment = any text
  | pregnancy_category = Used in pregnancy against [[Pregnancy-induced hypertension|PIH]]
  | PLLR = Some PLLR text

Dependence liability

Optional parameters Dependence liability and Addiction_liability allow opioids or benzodiazepines to be flagged with the risk of becoming dependent/addicted upon them, although in many cases this may be somewhat subjective. Drugs should be rated as Low, Medium, High or Extremely high:

| dependency_liability = High
| addiction_liabiliy = High

Licensing information

There are three major licensing authorities that make drug information easily accessible: Health Canada, the US Food and Drug Administration (FDA), and the European Medicines Agency (EMA). NB: In British English, "licence" is the noun, "to license" is the verb. In US English, the noun is "license" (see #ENGVAR).

The FDA "Label Information" and the EMA "Product Information", where available, are very detailed. There is material aimed at the professional and also plain-English consumer information. These are excellent reliable source for article information but also contains much that makes it a worthwhile "External link" since there is no way one can include all the info. Both sites work when using the brand name of the drug but the FDA site also allows searches with the generic name (active ingredient), which lists generic variants where they are licensed. Health Canada's site operates similarly to the FDA's site, with Canada-specific drug monographs and other information. The DailyMed site is a more user-friendly repository of primarily labeling information. For all sites except EMA, the use of the generic name of the drug is preferred whenever possible as this will list all brand and generic forms of the drug.

| licence_CA = <!-- Health Canada may use generic or brand name (generic name preferred) -->
| licence_EU = <!-- Any input here (like '=yes'), will give link by INN -->
| DailyMedID = <!-- DailyMed may use generic or brand name (generic name preferred) -->
| licence_US = <!-- or |license_US=; FDA may use generic or brand name (generic name preferred) -->

|licence_EU=yes will create a link to the EMA site, using the INN (i.e., INN, drug_name or article title). When the EMA used INN is different, enter its INN in |INN_EMA=.

Lists of products and the parameter term to use may be easily searched for:

• European Public Assessment Reports: SiteMap, authorised products A–Z: human, veterinary
• Licence EU (EMA): any input in |licence_EU= will give a link to the EMA page for the active substance (INN).
• Drugs@FDA Search by Drug Name or Active Ingredient

  Where items are composed of more than one word, licence_US requires an underscore '_' in place of any spaces; e.g. Acyclovir_Sodium.

Drug class

| class = any text

The drug class designates the family that this drug belongs to. Typically the chemical class (e.g., benzodiazepine), mechanism of action (e.g., beta blocker), mode of action (e.g., diuretic), and/or therapeutic class (e.g., analgesic). Hence this field may contain more than one drug class if appropriate (each preferably wiki linked).

ATC, ATCvet

Where the drug is not included in ATC coding system (as opposed to its value just not been entered into the template) then set ATC_prefix to 'none', and the article is automatically added to Category:Drugs not assigned an ATC code:

| ATC_prefix        = none

Additional ATC may be included with the optional |ATC_supplemental= parameter as a comma-separated list. ATC templates may be used to have these additional codes link to the relevant databases:

| ATC_supplemental ={{ATC|M02|AA15}}, {{ATC|S01|BC03}}

Adds the following linked codes:

For ATC - M02AA15, S01BC03

Veterinary drugs are placed in a slightly different classification system, ATCvet. The code may be specified as ATCvet by setting the parameter ATCvet to 'yes'. Do not include the leading 'Q' in ATC_prefix:

| ATCvet            = yes
| ATC_prefix        = N05
| ATC_suffix        = AX90

Legal status

See also: {{Infobox drug/legal status}} for extensive documentation.

Legal status allows to specify which controlling acts are active in various countries and organisations. Available parameters are |legal_AU, legal_BR, legal_CA, legal_DE, legal_NZ, legal_UK, legal_US, legal_EU, legal_UN=, and links are provided for standard input. Also, the parameters can have the suffix |..._comment=.

Also available is |legal_status=, which is general and allows any text. When using this parameter, consider adding geographical information on where this is law.

Example

Κυκλοφορία
Κυκλοφορία	AU: Μόνο σε φαρμακείο (S2) any text UK: General sales list (GSL, OTC) US: Schedule II and OTC in Oregon Not marketed in Asia

| legal_AU     = S2
| legal_AU_comment = any text
| legal_BR     = A1
| legal_BR_comment = any text
| legal_CA     = 
| legal_DE     = 
| legal_UK     = gsl
| legal_US     = Schedule II
| legal_US_comment = and OTC in Oregon
| legal_EU     =
| legal_UN     =
| legal_NZ     = 
| legal_status = Not marketed in Asia

Returns:

Note: if a drug is restricted everywhere to prescription-only, please set legal_status = Rx-only rather than similarly define for each and every country. |legal_status=Rx-only is specifically recognised and shows as

• ℞ (Prescription only)

Input	Meaning
legal_status	Anywhere
Rx-only	℞ Prescription only
legal_AU	Australia (see SUSDP)
Unscheduled	Unscheduled/exempt
S2	Schedule 2 Pharmacy Medicine
S3	Schedule 3 Pharmacist Only Medicine
S4	Schedule 4 Prescription Only Medicine
S5	Schedule 5 Caution
S6	Schedule 6 Poison
S7	Schedule 7 Dangerous Poison
S8	Schedule 8 Controlled Drug
S9	Schedule 9 Prohibited Substance
legal_BR	Brazil (see Controlled Drugs and Substances Act)
OTC	Over the counter
A1	Class A1: Narcotic Drugs
A2	Class A2: Narcotic Drugs
A3	Class A3: Psychoactive Drugs
B1	Class B1: Psychoactive Drugs
B2	Class B2: Anorectic Drugs
C1	Class C1: Other controlled substances
C2	Class C2: Retinoids
C3	Class C3: Immunosuppressive Drugs
C4	Class C4: Antiretroviral Drugs
C5	Class C5: Anabolic steroids
D1	Class D1: Drug precursors
D2	Class D2: Drug precursors
E	Class E: Controlled plants
F	Class F: Prohibited Substances
legal_CA	Canada
OTC	Over the counter
Rx-only	℞ Prescription only
Schedule I	See Controlled Drugs and Substances Act
Schedule II
Schedule III
Schedule IV
Schedule V
Schedule VI
Schedule VII
Schedule VIII
legal_UK	United Kingdom
GSL	General Sale List
P	Pharmacy Medicine
POM	Prescription Only Medicine
CD	Controlled Drug; if known may specify:
CD Lic	See Misuse of Drugs Regulations 2001 (as amended)
CD POM
CD No Reg POM
CD (Benz) POM
CD (Anab) POM
CD Inv POM
legal_US	United States
OTC	Over the counter
℞-only Rx-only	Prescription only; if appropriate may specify:
Schedule I	See Controlled Substances Act
Schedule II
Schedule III
Schedule IV
Schedule V
EU
UN
NZ

Pharmacokinetic data

In general, these parameters are relevant ro a drug. Use wikilinks for values that the general reader might not understand (e. g. hepatic, CYP3A4, intraperitoneal).

  | bioavailability   = 
  | protein_bound     = 
  | metabolism        = 
  | metabolites       =
  | onset             = 
  | elimination_half-life = 
  | duration_of_action= 
  | excretion         = 

Names and identifiers

AAN, BAN, JAN, USAN

Some countries have a variant INN name defined. For example, USAN (US) uses "acetaminophen" for paracetamol. Use |AAN= BAN= JAN= USAN= when a name is different from the INN (do not repeat INN).

CAS Registry Number

|CAS_number= Additional CAS codes may be included with optional |CAS_supplement= parameters in a comma-separated lists. CAS templates may be used to have these additional codes link to the relevant databases:

| CAS_supplemental ={{CAS|427-51-0}} (acetate)

Adds the following linked codes:

For CAS - 427-51-0 (acetate)

• See also: Second identifiers and indexes

DrugBank

The DrugBank primary accession number (consisting of a 2 letter prefix (DB) and a 5 number suffix). Secondary accession numbers with a 4 letter suffix (APRD, EXPT, BIOD, NUTR) should not normally be used.

PubChem

When available, the PubChem compound identifier (CID) should be used because it is unique for each chemical compound:

| PubChem        = 4091  <!-- Metformin -->

Make sure you choose the right CID: Often PubChem compound entries differ only very slightly, for example by an additional hydratation water or by a carbon atom with unspecified stereochemistry.

If no CID is available, which is usually the case when there is no structural information on PubChem, you may use one of the substance identifiers (SIDs):

| PubChemSubstance    = 10099  <!-- Etanercept -->

Second identifier (like: CAS_number2)

Chemical and physical data

Chemical formula

Entering the chemical formula per element:

| C= | H= | Ag= | Al= | As= | Au= | B= | Bi= | Br= | Ca= | Cl= | Co= | F= | Fe= | Gd= | I=
| K= | Li= | Mg= | Mn= | N= | Na= | O= | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn= 
<!-- all 118 symbols -->
| charge=
| chemical_formula_ref =
| chemical_formula_comment =

E.g.

| C=2 | H=6 | O=1 | charge=2-

gives

Formula C₂H₆O²⁻

This is called the empirical form, the most simple form. Entered this way, the elements are ordered in the Hill notation order: When C is present, C_xH_y in front and the others alphabetically Ar ... Zr. When a molecular formula or structural formula is known, that one should be entered in |chemical_formula= (consider using {{Chem}}).

You can provide the chemical formula as fixed

| chemical_formula =
| chemical_formula_ref =
| chemical_formula_comment =

todo: example

Molar mass

When the chemical formula is entered as |C=2 |O=1 |H=6, the molar mass is calculated and presented. This value can be overwritten by using |molecular_weight= (sic). For more information, see {{Chem molar mass}}.

Other chemical data

Additional chemical data fields are SMILES and standard InChI (optionally oncluding a comment and standard InChIKey).

| SMILES            =
| Jmol              =
| StdInChI          =
| StdInChI_comment  =
| StdInChIKey       =

The Jmol 3D model

When |SMILES= has input, the template automatically adds an external link to the Jmol 3D molecule model.

• |Jmol=None will suppress (hide) that data row.
• |Jmol=<some SMILES string> will link to the 3D-model of that string (i.e. overwriting |SMILES= input). SMILES will show its input unchanged.

Physical data

This is entirely optional data, and for most drugs is not helpful to the wider readership. Only include if information of particular interest for the drug as to its chemical properties (e.g. in its manufacture or as an important chemical in its own right, e.g. Aspirin).

| density           = 
| density_notes     =  
| melting_point     = 
| boiling_point     = 
| solubility        = 
| sol_units         = 
| specific_rotation = 

The template will add the following to the numeric values provided:

• Density - added 'g/cm³'
• Melting or Boiling points - added '°C' along with calculated converted value in °F.
• Solubility - If sol_units is specified, it will follow the solubility value; otherwise " mg/mL (20 °C)" will follow. This is to accommodate multiple solubility values at different temps, other units, etc.

Hence:

| solubility = 100
| sol_units  =  g/L ({{Convert|212|F|C}})

gives:

Solubility 100 g/L (212 °F (100 °C))

In addition, where the melting point occurs over a range of temperatures, use melting_high for the upper value.

Hence:

| melting_point = 100
| melting_high  = 104

gives:

Melting point 100–104 °C (212–219 °F)

Comments can be added to the melting and boiling point entries using melting_notes and boiling_notes.

Hence:

| boiling_point = 100
| boiling_notes = (sublimes)

gives:

Boiling point 100 °C (212 °F) (sublimes)

Physiological data (endogenous drugs)

Endogenous drugs (neurotransmitters, neurohormones, or hormones) are a single chemical (|type=<blank>). Their special data is shown in section "Physiological data".

Notes: input |metabolism= is shared with pharmacokinetic data, and will show in each of these sections that has more data (context).

When this section has input, sections Clinical data and Legal data should be empty.

<!-- Physiological data -->
| source_tissues = 
| target_tissues = 
| receptors      = 
| agonists       = 
| antagonists    = 
| precursor      = 
| biosynthesis   = 
| metabolism     = <!-- same parameter as in pharmacokinetic data -->

Example:

Oxytocin

Φαρμακοκινητική
Μεταβολισμός	oxytocinase

| drug_name      = [[Oxytocin]]
<!-- Physiological data -->
| source_tissues = [[posterior pituitary]]
| target_tissues = [[central nervous system]]
| receptors      = [[oxytocin receptor]]
| agonists       = [[carbetocin]], [[demoxytocin]]
| antagonists    = [[atosiban]], [[epelsiban]]
| precursor      = [[Neurophysin I|oxytocin-neurophysin 1]]
| biosynthesis   = [[magnolysin]]
| metabolism     = [[oxytocinase]]

Input from Wikidata

The template reads and shows the E number and ECHA InfoCard ID from Wikidata. If there is no value present, not no data is shown.

Miscellaneous

Verification by CheMoBot (parameters: ..._Ref)

Seven identfying parameters like |CAS_number=are tracked in a WP:Drugbox data validation process. A bot adds parameters like |verifiedrevid= and |CAS_number_Ref={{cascite|correct}}. See also {{cascite}} documentation.

English variant spellings (ENGVAR)

The word "License/Licence" can be spelled in two ways, generally by English variant en-UK or en-US. Per Manual of Style:ENGVAR, this chosen regional language should be consistent throughout the whole article.

The default spelling in the infobox is en-US: "LicenSe". Setting |engvar=en-AU, en-CA, en-EI, en-NZ, en-UK spells "LicenCe". Again, this should follow the article's overall language.

Independently from this, both either parameters |licence_US= or |license_US= can be used. This is for ease of editing, but does not change the spelling of "Licence/License" that will show.

Section overview by |type= options

A |type= can use specific headers.

| type=mab
| type=vaccine
| type=combo
| type=

Dependent sections: Πρότυπο:Infobox drug/doc/type-conditional sections

TemplateData

Tracking categories

See also

• {{Infobox medical condition}}
• ΒΠ:ΙΑΤΡ

Η παραπάνω τεκμηρίωση ενσωματώνεται από τη σελίδα Πρότυπο:Πληροφορίες φαρμάκου/τεκμηρίωση. (επεξεργασία | ιστορικό)
Οι συντάκτες μπορούν να πειραματίζονται στο πρόχειρο (δημιουργία | αντίγραφο) και στις δοκιμαστικές σελίδες (δημιουργία) του προτύπου.
Παρακαλούμε να προσθέτετε τις κατηγορίες στην υποσελίδα τεκμηρίωσης. Υποσελίδες αυτού του προτύπου.